144625-51-4

GR 113808 NLT 98%

Name: GR 113808
Brand: Molcore
SKU: MC524152
Rating: 96 (35 reviews)

SKU : MC524152

CAS Number : 144625-51-4

Molecular Formula : C19H27N3O4S | Molecular Weight : 393.50

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Purity	NLT 98%
Storage	at 20ºC 2 years

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Chemical Name	GR 113808
CAS Number	144625-51-4
MDL Number	MFCD00912901
Molecular Formula	C19H27N3O4S
Molecular Weight	393.50

Introduction of 144625-51-4 :

GR 113808 is a potent and highly selective 5-HT₄ receptor antagonist (pK_b= 8.8). GR 113808 shows 300-fold selectivity over 5-HT_1A, 5-HT_1B, 5-HT_2A, 5-HT_2C and 5-HT₃ receptors^[1]. In Vivo: GR113808 (intraperitoneal injection; 1 mg/kg; 5-7 days starting 24 h after induction of colitis) shows a significant increase in the disease activity index (DAI),which includes evaluation of weight loss, stool consistency, and presence of fecal blood^[2].

144625-51-4

GR 113808 NLT 98%

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