AG-825 NLT 98%
SKU : MC525513
CAS Number : 149092-50-2
Molecular Formula : C19H15N3O3S2 | Molecular Weight : 397.47
Synonyms : Tyrphostin AG-825
Quote Request| Purity | NLT 98% |
|---|---|
| Storage | at 20ºC 2 years |
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| Chemical Name | AG-825 |
|---|---|
| CAS Number | 149092-50-2 |
| MDL Number | MFCD01074971 |
| Molecular Formula | C19H15N3O3S2 |
| Molecular Weight | 397.47 |
| Synonyms | Tyrphostin AG-825 |
Introduction of 149092-50-2 :
AG-825 (Tyrphostin AG-825) is a selective and ATP-competitive ErbB2 inhibitor which suppresses tyrosine phosphorylation, with an IC50 of 0.35 μM. AG-825 displays anti-cancer activity[1][2][3]. AG825 significantly accelerates apoptosis of human neutrophils[4]. AG-825 is a potential agent for overcoming Mn-induced neurotoxicity or AD development[5]. IC50 & Target: IC50：0.35 μM (ErbB2), 19 μM (EGFR)[2]
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