SKU : MC529427
CAS Number : 163252-36-6
Molecular Formula : C10H13FN2O5 | Molecular Weight : 260.22
Quote RequestPurity | NLT 98% |
---|---|
Storage | at 20ºC 2 years |
* The above information is for reference only.
* If the product has intellectual property rights, a license granted is must or contact us.
Chemical Name | Clevudine |
---|---|
CAS Number | 163252-36-6 |
MDL Number | MFCD00935785 |
Molecular Formula | C10H13FN2O5 |
Molecular Weight | 260.22 |
Clevudine is an antiviral drug for the treatment of hepatitis B. Target: HBV Clevudine is a nucleoside analog with an unnatural beta-L configuration. Clevudine showed potent antiviral activity during therapy and induced a sustained posttreatment antiviral effect for 6 months after a 12-week treatment period, and this was associated with a sustained normalization of ALT levels [1]. Clevudine showed a potent antiviral response, and its effect was higher in HBeAg-negative patients, with rapid viral load reduction after therapy. However, long-term therapy for more than 1 year resulted in the development of considerable resistance and myopathy. Therefore, we should consider alternative antiviral agents if clevudine resistance or clevudine-induced myopathy is developed in patients on clevudine for the treatment of CHB [2].
© Copyright 2015-2024 Hangzhou MolCore BioPharmatech Co.,Ltd. All rights reserved.