Vofopitant dihydrochloride NLT 98%
SKU : MC530595
CAS Number : 168266-51-1
Molecular Formula : C21H25Cl2F3N6O | Molecular Weight : 505.36
Synonyms : GR 205171A
Quote Request| Purity | NLT 98% |
|---|---|
| Storage | at 20ºC 2 years |
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| Chemical Name | Vofopitant dihydrochloride |
|---|---|
| CAS Number | 168266-51-1 |
| MDL Number | MFCD00947113 |
| Molecular Formula | C21H25Cl2F3N6O |
| Molecular Weight | 505.36 |
| Synonyms | GR 205171A |
Introduction of 168266-51-1 :
Vofopitant dihydrochloride (GR 205171A) is a potent, selective and orally available tachykinin neurokinin 1(NK1) receptor antagonist, inhibits [3H]SP binding to the NK1 receptor with pKi values of 9.5 and 10.6 in rat and human membranes respectively, acts as a potential broad-spectrum anti-emetic agent[1]. IC50 & Target: pKi: 9.5 (NK1, rat), 10.6 (NK1, human)[1]
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