Zibotentan NLT 98%
SKU : MC534865
CAS Number : 186497-07-4
Molecular Formula : C19H16N6O4S | Molecular Weight : 424.43
Synonyms : ZD4054
Quote Request| Purity | NLT 98% |
|---|---|
| Storage | at 20ºC 2 years |
* The above information is for reference only.
* If the product has intellectual property rights, a license granted is must or contact us.
| Chemical Name | Zibotentan |
|---|---|
| CAS Number | 186497-07-4 |
| MDL Number | MFCD09955343 |
| Molecular Formula | C19H16N6O4S |
| Molecular Weight | 424.43 |
| Synonyms | ZD4054 |
Zibotentan (ZD4054) is an orally administered, potent and specific ETA-receptor (endothelin A receptor) antagonist (IC50 = 21 nM). IC50 value: 21 nM Target: ETA receptor Zibotentan is capable of inhibiting or reducing the multitude of effects that are evoked by ET-1 activation of the ETA receptor and which promote tumor survival, growth and progression. Zibotentan (ZD4054) treatment produced significant inhibition of tumor growth in ovarian and breast xenografts.
Related Products
© Copyright 2015-2024 Hangzhou MolCore BioPharmatech Co.,Ltd. All rights reserved.