(S,R,S)-AHPC-Me (hydrochloride) NLT 98%
Product Number : MC536475
CAS Number : 1948273-03-7
Molecular Formula : C23H32N4O3S | Molecular Weight : 444.59
Synonyms : VHL ligand 2 (hydrochloride);E3 ligase Ligand 1
Quote Request| Purity | NLT 98% |
|---|---|
| Storage | at 20ºC 2 years |
| MolCore specializes in manufacturing high-purity CAS No.1948273-03-7, (S,R,S)-AHPC-Me (hydrochloride) with the molecular formula C23H32N4O3S and molecular weight 444.59 delivering critical API intermediates for global pharmaceutical and research industries, certified under ISO quality systems. | |
* The above information is for reference only.
| Chemical Name | (S,R,S)-AHPC-Me (hydrochloride) |
|---|---|
| CAS Number | 1948273-03-7 |
| Molecular Formula | C23H32N4O3S |
| Molecular Weight | 444.59 |
| Synonyms | VHL ligand 2 (hydrochloride);E3 ligase Ligand 1 |
Introduction of 1948273-03-7 :
(S,R,S)-AHPC-Me hydrochloride (VHL ligand 2 hydrochloride) is the (S,R,S)-AHPC-based VHL ligand used in the recruitment of the von Hippel-Lindau (VHL) protein[1]. (S,R,S)-AHPC-Me hydrochloride can be used to synthesize ARV-771, a von Hippel-Landau (VHL) E3 ligase-based BET PROTAC degrader. ARV-771 potently degrades BET protein in castration-resistant prostate cancer (CRPC) cells with a DC50 <1 nM[2]. IC50 & Target: Ligand for E3 Ligase[1]
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