Deschloroclozapine NLT 98%
SKU : MC537088
CAS Number : 1977-07-7
Molecular Formula : C18H20N4 | Molecular Weight : 292.38
Quote Request| Purity | NLT 98% |
|---|---|
| Storage | at 20ºC 2 years |
* The above information is for reference only.
* If the product has intellectual property rights, a license granted is must or contact us.
| Chemical Name | Deschloroclozapine |
|---|---|
| CAS Number | 1977-07-7 |
| MDL Number | MFCD01730958 |
| Molecular Formula | C18H20N4 |
| Molecular Weight | 292.38 |
Deschloroclozapine is a potent and selective chemogenetic actuator. Deschloroclozapine is a dual dopamine and serotonin receptor antagonist with Kis of 200, 2500, 420, 39, 84, 40 nM for dopamine D1, D2,D4, and serotonin S2A, S2C, S3, respectively[1]. Deschloroclozapine is also a selective, high-affinity, metabolically stable, and brain-penetrable Designer Receptors Exclusively Activated by Designer Drug (DREADD) agonist[2]. IC50 & Target: Ki: 200 nM (Dopamne D1), 2500 nM (Dopamne D2), 420 nM (Dopamne D4), 39 nM (Serotonin S2A), 84 nM (Serotonin S2C), 200 nM (Serotonin S3)[1]
Related Products
© Copyright 2015-2024 Hangzhou MolCore BioPharmatech Co.,Ltd. All rights reserved.