Fmoc-Asp(2-phenylisopropyl ester)-OH 98% Min.
CAS Number : 200336-86-3
Molecular Formula : C28H27NO6 | Molecular Weight : 473.52 | MDL Number : MFCD00237012
Synonyms : Fmoc-Asp(OPp)-OH;Fmoc-Asp(O-2-PhiPr)-OH
An aspartic acid derivative allowing specific side chain deprotection with 1% TFA in dichloromethane. Ocampo et al. applied OPp protection during the synthesis of a peptide-oligonucleotide conjugate and cleaved it with 3% trichloroacetic acid in DCM. <br> The OPp derivative is far less prone towards base-catalyzed aspartimide formation than the OAll, OBzl, or ODmab esters, its stability comes close to the stability of the OtBu ester.
SKU : MC437141