Laninamivir NLT 98%
SKU : MC538052
CAS Number : 203120-17-6
Molecular Formula : C13H22N4O7 | Molecular Weight : 346.34
Synonyms : R 125489
Quote Request| Purity | NLT 98% |
|---|---|
| Storage | at 20ºC 2 years |
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| Chemical Name | Laninamivir |
|---|---|
| CAS Number | 203120-17-6 |
| MDL Number | MFCD18071611 |
| Molecular Formula | C13H22N4O7 |
| Molecular Weight | 346.34 |
| Synonyms | R 125489 |
Laninamivir (R 125489) is a potent influenza neuraminidase (NA) inhibitor with IC50s of 0.90 nM, 1.83 nM and 3.12 nM for avian H12N5 NA (N5), pH1N1 N1 NA (p09N1) and A/RI/5+/1957 H2N2 N2 (p57N2), respectively[1]. IC50 & Target: IC50: 0.90 nM (N5), 1.83 nM (p09N1), 3.12 nM (p57N2)[1] In Vitro: Laninamivir (R 125489) inhibits efficiently common oseltamivir-resistant viruses, including those with the ubiquitous His274Tyr substitution[1].
Laninamivir (R 125489) is potent against p57N2, p09N1 and N5 with a similar binding mode to Zanamivir[1].
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