SKU : MC540026
CAS Number : 211735-76-1
Molecular Formula : C12H13N3O2 | Molecular Weight : 231.25
Synonyms : CX-691;Org24448
Quote RequestPurity | NLT 98% |
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Storage | at 20ºC 2 years |
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Chemical Name | Farampator |
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CAS Number | 211735-76-1 |
MDL Number | MFCD00831010 |
Molecular Formula | C12H13N3O2 |
Molecular Weight | 231.25 |
Synonyms | CX-691;Org24448 |
Farampator (CX-691;Org24448) is an AMPA receptor positive modulator. In Vivo: Farampator has potential in treating disorders characterised by cognitive deficits such as Alzheimer's disease and schizophrenia. CX691 attenuates a scopolamine-induced impairment of cued fear conditioning following acute administration (0.1 mg/kg p.o.) and a temporally induced deficit in novel object recognition following both acute (0.1 and 1.0 mg/kg p.o.) and sub-chronic (bi-daily for 7 days) administration (0.01, 0.03, 0.1 mg/kg p.o.). It also improves attentional set-shifting following sub-chronic administration (0.3 mg/kg p.o.)[1]. Farampator (500 mg) unequivocally improves short-term memory but appeares to impair episodic memory. Furthermore, it tends to decrease the number of switching errors in the CTMT. Drug-induced side effects (SEs) included headache, somnolence and nausea. Subjects with SEs has significantly higher plasma levels of farampator than subjects without SEs[2].
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