NG 52 NLT 98%
SKU : MC540204
CAS Number : 212779-48-1
Molecular Formula : C16H19ClN6O | Molecular Weight : 346.81
Synonyms : Compound 52
Quote Request| Purity | NLT 98% |
|---|---|
| Storage | at 20ºC 2 years |
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| Chemical Name | NG 52 |
|---|---|
| CAS Number | 212779-48-1 |
| MDL Number | MFCD02179196 |
| Molecular Formula | C16H19ClN6O |
| Molecular Weight | 346.81 |
| Synonyms | Compound 52 |
NG 52 (Compound 52 ) is a potent, cell-permeable, reversible, selective, and ATP-compatible inhibitor of the cell cycle-regulating kinase, Cdc28p (IC50 = 7 μM), and the related Pho85p kinase (IC50 = 2 μM). IC50 value: 7 uM [1] Target: Cdc28p Compound 52 inhibited growth in a drug-sensitized yeast strain with a GI 50 of 30 uM. In contrast, the closely related compound 52Me proved to be a significantly weaker inhibitor of yeast growth (GI50=200 uM).
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