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220847-86-9 | Valategrast

Valategrast NLT 98%

Product Number : MC541729

CAS Number : 220847-86-9

Molecular Formula : C30H32Cl3N3O4 | Molecular Weight : 604.95

Synonyms : R-411 (free base)

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Purity NLT 98%
Storage at 20ºC 2 years
MolCore specializes in manufacturing high-purity CAS No.220847-86-9, Valategrast with the molecular formula C30H32Cl3N3O4 and molecular weight 604.95 delivering critical API intermediates for global pharmaceutical and research industries, certified under ISO quality systems.

* The above information is for reference only.

Chemical Name Valategrast
CAS Number 220847-86-9
MDL Number MFCD18782681
Molecular Formula C30H32Cl3N3O4
Molecular Weight 604.95
Synonyms R-411 (free base)
Introduction of 220847-86-9 :

Valategrast (R-411 free base) is a potent and orally active integrin α4β1 (VLA-4) and α4β7 dual antagonist. Valategrast has the potential for Chronic obstructive pulmonary disease (COPD) and asthma treatment[1][2]. IC50 & Target: Integrin α4β1; Integrin α4β7[2] In Vitro: Valategrast contains a common l-phenylalanine-N-aroyl motif where the carboxylic acid is responsible for binding to the metal ion in the metal-ion-dependent adhesion site (MIDAS)[2].