SKU : MC542258
CAS Number : 223488-57-1
Molecular Formula : C25H28N2O5S | Molecular Weight : 468.57
Synonyms : CP-533536 free acid
Quote RequestPurity | NLT 98% |
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Storage | at 20ºC 2 years |
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Chemical Name | Evatanepag |
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CAS Number | 223488-57-1 |
MDL Number | MFCD09833940 |
Molecular Formula | C25H28N2O5S |
Molecular Weight | 468.57 |
Synonyms | CP-533536 free acid |
Evatanepag (CP-533536) is an EP2 receptor selective prostaglandin E2 (PGE2) agonist that induces local bone formation with EC50 of 0.3 nM. IC50 value: 0.3 nM (EC50) Target PGE2 in vitro: CP-533536 is a potent and selective EP2agonist. CP-533536 demonstrates the ability to heal fractures when administered locally as a single dose in rat models of fracture healing. CP-533536 demonstrates excellent in vitro potency against EP2 and selectivity against a broad panel of other targets.
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