SKU : MC542273
CAS Number : 223568-55-6
Molecular Formula : C18H23FN2O6 | Molecular Weight : 382.38
Synonyms : F1013
Quote RequestPurity | NLT 98% |
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Storage | at 20ºC 2 years |
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Chemical Name | EP1013 |
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CAS Number | 223568-55-6 |
MDL Number | MFCD08457673 |
Molecular Formula | C18H23FN2O6 |
Molecular Weight | 382.38 |
Synonyms | F1013 |
EP1013 is a broad-spectrum caspase selective inhibitor, used in the research of type 1 diabetes. In Vivo: EP1013 (1, 3, 10 mg/kg) significantly improves marginal islet mass function. Two animals in the 10 mg/kg EP1013 treatment group exhibit primary islet graft nonfunction, but the diabetes reversal rate for this group is not significantly different from the 3 mg/kg EP1013, 1 mg/kg EP1013, or 10 mg/kg zVAD groups. EP1013 therapy enhances functional syngeneic islet mass and promotes longevity of islet graft function[1].
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