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22457-55-2 | 3-Phosphoglyceric acid (barium)

3-Phosphoglyceric acid (barium) NLT 98%

SKU : MC542416

CAS Number : 22457-55-2

Molecular Formula : C6H12BaO14P2 | Molecular Weight : 507.43

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Purity NLT 98%
Storage at 20ºC 2 years

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Chemical Name 3-Phosphoglyceric acid (barium)
CAS Number 22457-55-2
MDL Number MFCD00152754
Molecular Formula C6H12BaO14P2
Molecular Weight 507.43
Introduction of 22457-55-2 :

3-Phosphoglyceric acid barium is a metabolic intermediate in both glycolysis and the Calvin cycle. 3-Phosphoglyceric acid barium is involved in alveolar macrophage epigenetic regulation[1]. In Vitro: 3-Phosphoglyceric acid (400 µM; 24 hours; BMDMs) treatment enhances Spp1 transcription in VHL-deficient macrophages, and the reduced H3K4me3 modification is also reversed[1].
3-Phosphoglyceric treatment significantly augmentes gene expression as well as H3K4me3 deposition of Spp1 in IL-4-stimulated macrophages[1].
In yeast, 3-Phosphoglyceric acid acts as a metabolic checkpoint for the formation of a multicomponent enzyme complex including serine metabolic enzymes and pyruvate kinase isoform 2 (PKM2) homologue, which senses both serine metabolism and glycolysis and regulates H3K4 methylation and histone phosphorylation[1].

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