SKU : MC542416
CAS Number : 22457-55-2
Molecular Formula : C6H12BaO14P2 | Molecular Weight : 507.43
Quote RequestPurity | NLT 98% |
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Storage | at 20ºC 2 years |
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Chemical Name | 3-Phosphoglyceric acid (barium) |
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CAS Number | 22457-55-2 |
MDL Number | MFCD00152754 |
Molecular Formula | C6H12BaO14P2 |
Molecular Weight | 507.43 |
3-Phosphoglyceric acid barium is a metabolic intermediate in both glycolysis and the Calvin cycle. 3-Phosphoglyceric acid barium is involved in alveolar macrophage epigenetic regulation[1]. In Vitro: 3-Phosphoglyceric acid (400 µM; 24 hours; BMDMs) treatment enhances Spp1 transcription in VHL-deficient macrophages, and the reduced H3K4me3 modification is also reversed[1].
3-Phosphoglyceric treatment significantly augmentes gene expression as well as H3K4me3 deposition of Spp1 in IL-4-stimulated macrophages[1].
In yeast, 3-Phosphoglyceric acid acts as a metabolic checkpoint for the formation of a multicomponent enzyme complex including serine metabolic enzymes and pyruvate kinase isoform 2 (PKM2) homologue, which senses both serine metabolism and glycolysis and regulates H3K4 methylation and histone phosphorylation[1].
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