Tel: +86 (0)571 8102-5280 Email:
224785-91-5 | Vardenafil (hydrochloride)

Vardenafil (hydrochloride) NLT 98%

SKU : MC542443

CAS Number : 224785-91-5

Molecular Formula : C23H33ClN6O4S | Molecular Weight : 525.06

Quote Request
Purity NLT 98%
Storage at 20ºC 2 years

* The above information is for reference only.

* If the product has intellectual property rights, a license granted is must or contact us.

Chemical Name Vardenafil (hydrochloride)
CAS Number 224785-91-5
MDL Number MFCD07369690
Molecular Formula C23H33ClN6O4S
Molecular Weight 525.06
Introduction of 224785-91-5 :

Vardenafil Hcl is a PDE5 inhibitor used for treating erectile dysfunction. Target: PDE5 Vardenafil specifically inhibited the hydrolysis of cGMP by PDE5 with an IC50 of 0.7 nM (6.6 nM). In contrast, the IC50 of vardenafil for PDE1 was 180 nM; for PDE6, 11 nM; for PDE2, PDE3 and PDE4, more than 1000 nM. Relative to PDE5, the ratios of the IC50 for PDE1 were 257 (60), for PDE6 16 (7.4). Vardenafil significantly enhanced the SNP-induced relaxation of human trabecular smooth muscle at 3 nM (10 nM). Vardenafil also significantly potentiated both ACh-induced and transmural electrical stimulation-induced relaxation of trabecular smooth muscle [1]. Both vardenafil doses(10 mg or 20 mg) significantly enhanced the

Related Products