SKU : MC542453
CAS Number : 22494-47-9
Molecular Formula : C17H17ClO3 | Molecular Weight : 304.77
Synonyms : ICI 55897;Clobuzarit
Quote RequestPurity | NLT 98% |
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Storage | at 20ºC 2 years |
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Chemical Name | Clozic |
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CAS Number | 22494-47-9 |
MDL Number | MFCD00866720 |
Molecular Formula | C17H17ClO3 |
Molecular Weight | 304.77 |
Synonyms | ICI 55897;Clobuzarit |
Clozic is a potential anti-arthritic agent. In Vitro: Clozic is a potential anti-arthritic agent. Concentrations of Clozic greater than 50 μM cause a dose-dependent decrease in the amount of matrix protein synthesized by RHMC cell cultures. Inhibition of RHMC cell culture growth by Clozic occurs in a dose-dependent manner. The anti-proliferative effect of Clozic on RHMC cell growth is reversible. Lactate dehydrogenase (LDH) levels in media taken from RHMC cell cultures exposed to 500 μM Clozic for 3 days do not significantly differ from LDH levels in control cell culture media[1].
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