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22494-47-9 | Clozic

Clozic NLT 98%

SKU : MC542453

CAS Number : 22494-47-9

Molecular Formula : C17H17ClO3 | Molecular Weight : 304.77

Synonyms : ICI 55897;Clobuzarit

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Purity NLT 98%
Storage at 20ºC 2 years

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Chemical Name Clozic
CAS Number 22494-47-9
MDL Number MFCD00866720
Molecular Formula C17H17ClO3
Molecular Weight 304.77
Synonyms ICI 55897;Clobuzarit
Introduction of 22494-47-9 :

Clozic is a potential anti-arthritic agent. In Vitro: Clozic is a potential anti-arthritic agent. Concentrations of Clozic greater than 50 μM cause a dose-dependent decrease in the amount of matrix protein synthesized by RHMC cell cultures. Inhibition of RHMC cell culture growth by Clozic occurs in a dose-dependent manner. The anti-proliferative effect of Clozic on RHMC cell growth is reversible. Lactate dehydrogenase (LDH) levels in media taken from RHMC cell cultures exposed to 500 μM Clozic for 3 days do not significantly differ from LDH levels in control cell culture media[1].

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