Hydroxy desmethyl Bosentan NLT 98%
Product Number : MC544558
CAS Number : 253688-62-9
Molecular Formula : C26H27N5O7S | Molecular Weight : 553.59
Synonyms : Ro 64-1056
Quote Request| Purity | NLT 98% |
|---|---|
| Storage | at 20ºC 2 years |
| MolCore specializes in manufacturing high-purity CAS No.253688-62-9, Hydroxy desmethyl Bosentan with the molecular formula C26H27N5O7S and molecular weight 553.59 delivering critical API intermediates for global pharmaceutical and research industries, certified under ISO quality systems. | |
* The above information is for reference only.
| Chemical Name | Hydroxy desmethyl Bosentan |
|---|---|
| CAS Number | 253688-62-9 |
| MDL Number | MFCD09840720 |
| Molecular Formula | C26H27N5O7S |
| Molecular Weight | 553.59 |
| Synonyms | Ro 64-1056 |
Introduction of 253688-62-9 :
Hydroxy desmethyl Bosentan (Ro 64-105) is a Bosentan metabolism produced by the cytochrome P450 enzymes CYP2C9 and CYP3A4 in the liver[1]. Bosentan is a competitive and dual antagonist of endothelin-1 (ET) for the ETA and ETB receptors with Ki of 4.7 nM and 95 nM in human SMC, respectively. Bosentan can be used in treatment of pulmonary arterial hypertension[2].
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