SKU : MC544597
CAS Number : 25422-31-5
Molecular Formula : C63H97N19O26 | Molecular Weight : 1536.56
Synonyms : Human fibrinopeptide A
Quote RequestPurity | NLT 98% |
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Storage | at 20ºC 2 years |
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Chemical Name | Fibrinopeptide A, human |
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CAS Number | 25422-31-5 |
MDL Number | MFCD00076437 |
Molecular Formula | C63H97N19O26 |
Molecular Weight | 1536.56 |
Synonyms | Human fibrinopeptide A |
Fibrinopeptide A, human is a 16-residue short polypeptide cleaved from fibrinogen by thrombin. Fibrinopeptide A, human locates at the NH2-termini of the Aα chain. In Vitro: The conversion of monomeric fibrinogen into polymeric fibrin is mediated by thrombin, which binds to the central region of fibrinogen and catalyzes cleavage of the 2 short peptides, the 16-residue fibrinopeptide A (FpA) and the 14-residue fibrinopeptide B (FpB), located at the NH2-termini of the Aα and Bβ chains, respectively[1]. In Vivo: Fibrinopeptide A (FPA) is a small polypeptide cleaved from fibrinogen by thrombin, has a short half-life, and is considered a sensitive biochemical marker of thrombin activity, fibrin generation, and ongoing thrombosis[2].
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