SKU : MC544951
CAS Number : 26001-32-1
Molecular Formula : C16H27N3O4 | Molecular Weight : 325.40
Quote RequestPurity | NLT 98% |
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Storage | at 20ºC 2 years |
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Chemical Name | H-Ile-Pro-Pro-OH |
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CAS Number | 26001-32-1 |
MDL Number | MFCD08458621 |
Molecular Formula | C16H27N3O4 |
Molecular Weight | 325.40 |
H-Ile-Pro-Pro-OH, a milk-derived peptide[1], inhibits angiotensin-converting enzyme (ACE)[1] with an IC50 of 5 μM[2]. Antihypertensive tripeptides[1]. IC50 & Target: IC50: 5 μM (ACE)[2] In Vitro: Vitro: Ile-Pro-Pro (IPP) increases nitric oxide (NO) production in human umbilical vein endothelial cells (HUVECs)[1]. In Vivo: Vivo: Ile-Pro-Pro attenuates arterial dysfunction in L-NAME-treated rats[1]
Ile-Pro-Pro (IPP) decreases blood pressure in spontaneously hypertensive rats (SHR) [1].
Ile-Pro-Pro (IPP) attenuates the development of atherosclerosis in apolipoprotein E-deficient (apoE(-/-)) mice[1].
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