Fmoc-Orn(Dde)-OH NLT 98%
SKU : MC437487
CAS Number : 269062-80-8
Molecular Formula : C30H34N2O6 | Molecular Weight : 518.60
Quote Request| Purity | NLT 98% |
|---|---|
| Storage | -20 ± 5 ºC |
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| Chemical Name | Fmoc-Orn(Dde)-OH |
|---|---|
| CAS Number | 269062-80-8 |
| MDL Number | MFCD01862895 |
| Molecular Formula | C30H34N2O6 |
| Molecular Weight | 518.60 |
The Nδ-protecting group Dde is orthogonal to both Fmoc and Boc which allows on-resin modification of ornithine side chains during Fmoc/tBu-based SPPS. The applications of Dde side-chain protection include synthesis of branched or di-epitopic peptides, preparation of MAP core molecules and lipo-MAPS, the synthesis of cyclic peptides, TASP molecules, and templates for combinatorial chemistry and synthetic proteins. Dde can be cleaved by 2% hydrazine in DMF.
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