Fmoc-Asp(ODmab)-OH NLT 98%
SKU : MC437133
CAS Number : 269066-08-2
Molecular Formula : C39H42N2O8 | Molecular Weight : 666.76
Quote Request| Purity | NLT 98% |
|---|---|
| Storage | -20 ± 5 ºC |
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| Chemical Name | Fmoc-Asp(ODmab)-OH |
|---|---|
| CAS Number | 269066-08-2 |
| MDL Number | MFCD00797875 |
| Molecular Formula | C39H42N2O8 |
| Molecular Weight | 666.76 |
Dmab can be removed with 2% hydrazine in DMF generating an indazole which allows the UV-spectrophotometrical monitoring of the cleavage. Conroy et al. used this Asp derivative for the solid-phase synthesis of N-linked glycopeptides.
As Dmab represents an unhindered p-substituted Z-derivative, Asp(Dmab)-containing peptides are prone to base-catalyzed aspartimide formation.
As Dmab represents an unhindered p-substituted Z-derivative, Asp(Dmab)-containing peptides are prone to base-catalyzed aspartimide formation.
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