SKU : MC546631
CAS Number : 28978-02-1
Molecular Formula : C29H34O15 | Molecular Weight : 622.57
Quote RequestPurity | NLT 98% |
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Storage | at 20ºC 2 years |
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Chemical Name | Pectolinarin |
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CAS Number | 28978-02-1 |
MDL Number | MFCD12407436 |
Molecular Formula | C29H34O15 |
Molecular Weight | 622.57 |
Pectolinarin, isolated from Cirsium chanroenicum, possesses anti-inflammatory activity[1]. Pectolinarin inhibits secretion of IL-6 and IL-8, as well as the production of PGE2 and NO. Pectolinarin suppresses cell proliferation and inflammatory response and induces apoptosis via inactivation of the PI3K/Akt pathway[2]. In Vitro: Pectolinarin increases Bax level, and decreases Bcl-2 level in rheumatoid arthritis fibroblast-like synoviocytes (RA-FLSs). Pectolinarin inactivates the PI3K/Akt pathway in RA-FLSs[2].
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