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28978-02-1 | Pectolinarin

Pectolinarin NLT 98%

SKU : MC546631

CAS Number : 28978-02-1

Molecular Formula : C29H34O15 | Molecular Weight : 622.57

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Purity NLT 98%
Storage at 20ºC 2 years

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Chemical Name Pectolinarin
CAS Number 28978-02-1
MDL Number MFCD12407436
Molecular Formula C29H34O15
Molecular Weight 622.57
Introduction of 28978-02-1 :

Pectolinarin, isolated from Cirsium chanroenicum, possesses anti-inflammatory activity[1]. Pectolinarin inhibits secretion of IL-6 and IL-8, as well as the production of PGE2 and NO. Pectolinarin suppresses cell proliferation and inflammatory response and induces apoptosis via inactivation of the PI3K/Akt pathway[2]. In Vitro: Pectolinarin increases Bax level, and decreases Bcl-2 level in rheumatoid arthritis fibroblast-like synoviocytes (RA-FLSs). Pectolinarin inactivates the PI3K/Akt pathway in RA-FLSs[2].

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