SKU : MC547028
CAS Number : 2980-32-7
Molecular Formula : C13H8O6 | Molecular Weight : 260.20
Synonyms : Desmethylbellidifolin
Quote RequestPurity | NLT 98% |
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Storage | at 20ºC 2 years |
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Chemical Name | 1,3,5,8-Tetrahydroxyxanthone |
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CAS Number | 2980-32-7 |
Molecular Formula | C13H8O6 |
Molecular Weight | 260.20 |
Synonyms | Desmethylbellidifolin |
1,3,5,8-Tetrahydroxyxanthone (Desmethylbellidifolin) is a natural xanthone extracted from Gentianella acuta. 1,3,5,8-Tetrahydroxyxanthone has antispasmodic effect and anti-inflammatory activity[1]. In Vitro: 1,3,5,8-Tetrahydroxyxanthone (Desmethylbellidifolin) attenuates lipopolysaccharide-induced nitric oxide release and proinflammatory cytokine expression in RAW264.7 cells[1]. In Vivo: 1,3,5,8-Tetrahydroxyxanthone (Desmethylbellidifolin; orally; 5, 10, 20 mg/kg; 12 days) can inhibit trinitrobenzenesulfonic acid (TNBS)-induced ulcerative colitis (UC), reducing inflammatory response and alleviate colon muscle spasm[1].
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