SKU : MC547135
CAS Number : 29976-75-8
Molecular Formula : C16H12O2 | Molecular Weight : 236.27
Quote RequestPurity | NLT 98% |
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Storage | at 20ºC 2 years |
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Chemical Name | 6-Methylflavone |
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CAS Number | 29976-75-8 |
Molecular Formula | C16H12O2 |
Molecular Weight | 236.27 |
6-Methylflavone is an activator of α1β2γ2L and α1β2 GABAA receptors. IC50 & Target: α1β2γ2L GABAA receptor, α1β2 GABAA receptor[1] In Vitro: 6-Methylflavone is an activator of α1β2γ2L and α1β2 GABAA receptors. 6-Methylflavone enhances the normal response to GABA at recombinant α1β2γ2L and α1β2 GABAA receptors (P<0.0001) at concentrations from 1 to 100 μM. 6-Methylflavone (60 μM) shifts the GABA dose-response curve to the left (n=4, F=16.38, P=0.0004), decreasing the mean EC50 at α1β2γ2L GABAA receptors by 33±5.4%[1].
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