UBP 1112 NLT 98%
Product Number : MC549615
CAS Number : 339526-74-8
Molecular Formula : C10H14NO5P | Molecular Weight : 259.20
Quote Request| Purity | NLT 98% |
|---|---|
| Storage | at 20ºC 2 years |
| MolCore specializes in manufacturing high-purity CAS No.339526-74-8, UBP 1112 with the molecular formula C10H14NO5P and molecular weight 259.20 delivering critical API intermediates for global pharmaceutical and research industries, certified under ISO quality systems. | |
* The above information is for reference only.
| Chemical Name | UBP 1112 |
|---|---|
| CAS Number | 339526-74-8 |
| MDL Number | MFCD06798363 |
| Molecular Formula | C10H14NO5P |
| Molecular Weight | 259.20 |
UBP 1112 is a selective group III mGluR antagonist, with a Kd of 5.1 μM, 96-fold affinity for group III over group II mGlu receptor (Kd, 488 μM), and shows no significant activity at group I mGlu receptor or iGlu receptor. IC50 & Target: Kd: 5.1 μM (group III mGluR), 488 μM (group II mGluR)[1] In Vitro: UBP 1112 is a group III mGluR antagonist, with a Kd of 5.1 μM, 96-fold affinity for group III over group II mGlu receptor (Kd, 488 μM), and shows no significant activity at group I mGlu receptor or iGlu receptor. UBP 1112 antagonises the depression of the fast component of the dorsal root-evoked ventral root potential induced by (S)-AP4 with apparent KD of 5.1±0.3 μM. UBP 1112 also antagonises the (S)-AP4 induced depression of synaptic transmission, with pA2 of 5.3. In addition, UBP 1112 (1 mM) displays little or no activity on (S)-3,5-DHPG-, NMDA-, AMPA- or kainate-induced responses on motoneurones[1].
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