SKU : MC549918
CAS Number : 34391-04-3
Molecular Formula : C13H21NO3 | Molecular Weight : 239.31
Synonyms : (R)-Albuterol;(R)-Salbutamol;Levosalbutamol
Quote RequestPurity | NLT 98% |
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Storage | at 20ºC 2 years |
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Chemical Name | Levalbuterol |
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CAS Number | 34391-04-3 |
MDL Number | MFCD00869868 |
Molecular Formula | C13H21NO3 |
Molecular Weight | 239.31 |
Synonyms | (R)-Albuterol;(R)-Salbutamol;Levosalbutamol |
Levalbuterol ((R)-Albuterol; (R)-Salbutamol) is a short-acting β2-adrenergic receptor agonist and the active (R)-enantiomer of Salbutamol. Levalbuterol is a more potent bronchodilator than Salbutamol and has the potential for the treatment of COPD[1].
In Vitro: Levalbuterol (10 μM; 24 hours) induces 11β-HSD1 mRNA expression, however, it does not influence 11β-HSD2expression in airway epithelial cells[1].
Levalbuterol (10 μM; 24 hours) significantly reduces both LPS- and TNF-α-induced NF-κB activity while increasing GRE activation in an 11β-HSD1 dependent manner in a transformed mouse airway epithelial cell line[1].
In Vivo: Levalbuterol (subcutaneous injection; 1 mg/kg; 14 days) significantly decreases pulmonary inflammation in OVA mice, demonstrated a decrease in eosinophilia and IgE[3].
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