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35865-33-9 | Dianemycin

Dianemycin NLT 98%

SKU : MC550906

CAS Number : 35865-33-9

Molecular Formula : C47H78O14 | Molecular Weight : 867.11

Synonyms : Nanchangmycin (free acid)

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Purity NLT 98%
Storage at 20ºC 2 years

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Chemical Name Dianemycin
CAS Number 35865-33-9
MDL Number MFCD01736187
Molecular Formula C47H78O14
Molecular Weight 867.11
Synonyms Nanchangmycin (free acid)
Introduction of 35865-33-9 :

Dianemycin (Nanchangmycin free acid), a polyether antibiotic produced by Streptomyces nanchangensis NS3226, inhibits gram-positive bacteria[1]. Nanchangmycin is a broad spectrum antiviral active against Zika virus[2]. IC50 & Target: Bacteria[1]
Zika virus[2] In Vitro: Dianemycin (Nanchangmycin) can be used as a growth promotant in poultry and to cure coccidiosis in chickens. Dianemycin is active against drug resistant strains of malaria[1].
Dianemycin (Nanchangmycin) as a potent inhibitor of Zika virus (ZIKV) entry across all cell types tested including physiologically relevant primary cells. Dianemycin potently reduces infection of all three strains of ZIKV across all three cell types. The IC50s for infection are between 0.1 and 0.4 μM while Dianemycin has low toxicity in these ranges. In addition, DENV is inhibited by Dianemycin across cell types[2].

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