SKU : MC552007
CAS Number : 3776-39-4
Molecular Formula : C20H26O6 | Molecular Weight : 362.42
Quote RequestPurity | NLT 98% |
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Storage | at 20ºC 2 years |
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Chemical Name | Enmein |
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CAS Number | 3776-39-4 |
MDL Number | MFCD01714945 |
Molecular Formula | C20H26O6 |
Molecular Weight | 362.42 |
Enmein is isolated from I. serra with immunosuppressive effect[1]. In Vitro: Enmein shows significant inhibitory effect toward K562 with an IC50 value ranging from 3.2 μg/ml to 8.2 μg/ml[2].
Enmein (3.13-25 μg/ml; 48 hours) has inhibitory effect on lymphocytes with significant difference within concentration from 6.25 μg/ml to 25 μg/ml[1].
Enmein (5.5-22 μg/ml; 48 hours) causes the percentage of S stage cells decreased from 19% to 6%, causes the percentage of G2/M stage cells to decrease from 2% to 0.4%[1].
In Vivo: Enmein (inject to ear; 6.52-13.04 mg/kg; 5 days) inhibits the xylene-induced ear swelling and inhibits IL-2 expression[1].
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