Zaprinast NLT 98%
SKU : MC552009
CAS Number : 37762-06-4
Molecular Formula : C13H13N5O2 | Molecular Weight : 271.27
Synonyms : M&B 22948
Quote Request| Purity | NLT 98% |
|---|---|
| Storage | at 20ºC 2 years |
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| Chemical Name | Zaprinast |
|---|---|
| CAS Number | 37762-06-4 |
| MDL Number | MFCD00214073 |
| Molecular Formula | C13H13N5O2 |
| Molecular Weight | 271.27 |
| Synonyms | M&B 22948 |
Introduction of 37762-06-4 :
Zaprinast (M&B 22948) is an inhibitor of cGMP-selective Phosphodiesterases(PDEs)[1]. Zaprinast is a G protein-coupled receptor (GPR) 35 agonist which activates rat GPR35 strongly and activates human GPR35 moderately[2]. Zaprinast reduces vessel remodeling through antiproliferative and proapoptotic effects[3]. IC50 & Target: PDE[1], GPR35[2]
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