Zinterol hydrochloride NLT 98%
SKU : MC552289
CAS Number : 38241-28-0
Molecular Formula : C19H27ClN2O4S | Molecular Weight : 414.95
Synonyms : MJ 9184 hydrochloride
Quote Request| Purity | NLT 98% |
|---|---|
| Storage | at 20ºC 2 years |
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| Chemical Name | Zinterol hydrochloride |
|---|---|
| CAS Number | 38241-28-0 |
| MDL Number | MFCD01715339 |
| Molecular Formula | C19H27ClN2O4S |
| Molecular Weight | 414.95 |
| Synonyms | MJ 9184 hydrochloride |
Zinterol hydrochloride (MJ 9184 hydrochloride) is a potent and selective β2-adrenoceptor agonist[1]. Zinterol increases ICa in a concentration-dependent manner with an EC50 of 2.2 nM[2]. IC50 & Target: β2-adrenoceptor[1] In Vivo: Zinterol (2.5 μg/kg i.v. bolus over 5 s) leads to ventricular arrhythmias including premature ventricular complexes (PVCs) and runs of ventricular tachycardia (VT) in heart failure (HF) rabbits. Zinterol at a lower dose (1 μg/kg i.v, n=4) does not induce ventricular arrhythmias in HF rabbits[3].
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