Fmoc-Asp(OtBu)-(Hmb)Gly-OH NLT 98%
Product Number : MC437136
CAS Number : 502640-94-0
Molecular Formula : C33H36N2O9 | Molecular Weight : 604.65
Synonyms : Fmoc-Asp(OtBu)-N-(2-hydroxy-4-methoxy-Bzl)-Gly-OH
Quote Request| Purity | NLT 98% |
|---|---|
| Storage | -20 ± 5 ºC |
| MolCore specializes in manufacturing high-purity CAS No.502640-94-0, Fmoc-Asp(OtBu)-(Hmb)Gly-OH with the molecular formula C33H36N2O9 and molecular weight 604.65 delivering critical API intermediates for global pharmaceutical and research industries, certified under ISO quality systems. | |
* The above information is for reference only.
| Chemical Name | Fmoc-Asp(OtBu)-(Hmb)Gly-OH |
|---|---|
| CAS Number | 502640-94-0 |
| MDL Number | MFCD06656487 |
| Molecular Formula | C33H36N2O9 |
| Molecular Weight | 604.65 |
| Synonyms | Fmoc-Asp(OtBu)-N-(2-hydroxy-4-methoxy-Bzl)-Gly-OH |
Aspartimide formation of the highly base-labile Asp-Gly motif during Fmoc-SPPS may be completely suppressed by coupling this Hmb-protected dipeptide derivative. Additionally, Hmb prevents aggregation of the growing peptide chain as efficiently as the incorporation of a pseudoproline moiety. O-Acylation renders the Hmb moiety acid-stable facilitating the purification of peptides prone to form aggregates. The acyl group can be removed with hydrazine hydrate in DMF (cf. Quibell).
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