H-Lys(acetimidoyl)-OH NLT 98%
SKU : MC437855
CAS Number : 53774-63-3
Molecular Formula : C8H17N3O2 | Molecular Weight : 187.24
Synonyms : L-NIL;H-Lys(1-iminoethyl)-OH;N-(5-Amino-5-carboxypentyl)-acetamidine
Quote Request| Purity | NLT 98% |
|---|---|
| Storage | -20 ± 5 ºC |
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| Chemical Name | H-Lys(acetimidoyl)-OH |
|---|---|
| CAS Number | 53774-63-3 |
| MDL Number | MFCD00792818 |
| Molecular Formula | C8H17N3O2 |
| Molecular Weight | 187.24 |
| Synonyms | L-NIL;H-Lys(1-iminoethyl)-OH;N-(5-Amino-5-carboxypentyl)-acetamidine |
L-NIL inhibited mouse inducible nitric oxide synthase with an IC₅₀ of 3.3 µM compared to an IC₅₀ of 92 µM obtained for rat brain constitutive NOS. The lysine-derived inhibitor may be useful as a selective and potent inhibitor of inducible NOS for determining the role of this enzyme in disease models (e.g. chronic inflammation and autoimmune diseases). Bryk et al. studied the suicidal disactivation of neuronal NOS by L-NIL.
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