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76996-27-5 | Garcinone C

Garcinone C NLT 98%

SKU : MC571123

CAS Number : 76996-27-5

Molecular Formula : C23H26O7 | Molecular Weight : 414.45

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Purity NLT 98%
Storage at 20ºC 2 years

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Chemical Name Garcinone C
CAS Number 76996-27-5
MDL Number MFCD11111285
Molecular Formula C23H26O7
Molecular Weight 414.45
Introduction of 76996-27-5 :

Garcinone C, a xanthone derivative, is a natural compound extracted from Garcinia oblongifolia Champ that is used as an anti-inflammatory, analgesia, astringency and granulation-promoting medicine, and has potential cytotoxic effects on certain cancers. Garcinone C stimulates the expression levels of ATR and 4E-BP1, while efficiently inhibiting the expression levels of cyclin B1, cyclin D1, cyclin E2, cdc2, Stat3 and CDK7. Garcinone C significantly inhibits cell viability of the human Nasopharyngeal carcinoma (NPC) cell lines CNE1, CNE2, HK1 and HONE1 in a time‑ and dose‑dependent manner[1].

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