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77-53-2 | Cedrol

Cedrol NLT 98%

SKU : MC571143

CAS Number : 77-53-2

Molecular Formula : C15H26O | Molecular Weight : 222.37

Synonyms : (+)-Cedrol;α-Cedrol

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Purity NLT 98%
Storage at 20ºC 2 years

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Chemical Name Cedrol
CAS Number 77-53-2
MDL Number MFCD00062952
Molecular Formula C15H26O
Molecular Weight 222.37
Synonyms (+)-Cedrol;α-Cedrol
Introduction of 77-53-2 :

Cedrol is a bioactive sesquiterpene, a potent competitive inhibitor of cytochrome P-450 (CYP) enzymes. Cedrol inhibits CYP2B6-mediated bupropion hydroxylase and CYP3A4-mediated midazolam hydroxylation with Ki of 0.9 μM and 3.4 μM, respectively. Cedrol also has weak inhibitory effect on CYP2C8, CYP2C9, and CYP2C19 enzymes[1]. Cedrol is found in cedar essential oil and poetesses anti-septic, anti-inflammatory, anti-spasmodic, tonic, astringent, diuretic, sedative, insecticidal, and anti-fungal activities[2]. IC50 & Target: CYP2B6; CYP3A4; CYP2C8; CYP2C9; CYP2C19[1]

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