SKU : MC571143
CAS Number : 77-53-2
Molecular Formula : C15H26O | Molecular Weight : 222.37
Synonyms : (+)-Cedrol;α-Cedrol
Quote RequestPurity | NLT 98% |
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Storage | at 20ºC 2 years |
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Chemical Name | Cedrol |
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CAS Number | 77-53-2 |
MDL Number | MFCD00062952 |
Molecular Formula | C15H26O |
Molecular Weight | 222.37 |
Synonyms | (+)-Cedrol;α-Cedrol |
Cedrol is a bioactive sesquiterpene, a potent competitive inhibitor of cytochrome P-450 (CYP) enzymes. Cedrol inhibits CYP2B6-mediated bupropion hydroxylase and CYP3A4-mediated midazolam hydroxylation with Ki of 0.9 μM and 3.4 μM, respectively. Cedrol also has weak inhibitory effect on CYP2C8, CYP2C9, and CYP2C19 enzymes[1]. Cedrol is found in cedar essential oil and poetesses anti-septic, anti-inflammatory, anti-spasmodic, tonic, astringent, diuretic, sedative, insecticidal, and anti-fungal activities[2]. IC50 & Target: CYP2B6; CYP3A4; CYP2C8; CYP2C9; CYP2C19[1]
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