Fmoc-Pro-DHPP resin (200-400 mesh) 98% Min.
Product Number : MC437516
Quote Request| Purity | 98% Min. |
|---|---|
| Storage | +5 ± 3 ºC |
| MolCore specializes in manufacturing high-purity Fmoc-Pro-DHPP resin (200-400 mesh) with the molecular formula null and molecular weight null delivering critical API intermediates for global pharmaceutical and research industries, certified under ISO quality systems. | |
* The above information is for reference only.
| Chemical Name | Fmoc-Pro-DHPP resin (200-400 mesh) |
|---|
DHPP-resin, i.e. 4-(1',1'-dimethyl-1'-hydroxypropyl)phenoxyacetyl-alanyl-aminomethyl resin, has been developed especially for the synthesis of peptides containing a C-terminal proline. The bulkiness of the linker prevents diketopiperazine formation. As the esterification of Fmoc-Pro-OH (yielding a modified t-butyl ester) is impeded as well, the resin is offered as loaded derivative. Peptides can be cleaved from this resin applying the standard protocols for the cleavage from Wang resin.
Fmoc-Pro-DHPP-resin is an alternative to H-Pro-ClTrt-resin (D-2000) not only if an increased acid stability is required. The resin is more polar than 2-chlorotrityl resin and the Pro residue is more accessible.
Fmoc-Pro-DHPP-resin is an alternative to H-Pro-ClTrt-resin (D-2000) not only if an increased acid stability is required. The resin is more polar than 2-chlorotrityl resin and the Pro residue is more accessible.
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